Site Manager (San Francisco)

About Plasmidsaurus

Plasmidsaurus is on a mission to accelerate new cures and promote a healthier planet by unlocking a new level of productivity for scientists. Our sequencing services are used daily by thousands of innovators, including Nobel laureates, Fortune 100 pharma, and over 70,000 scientists.

We began by revolutionizing plasmid sequencing, making it exponentially cheaper and faster, with innovative sequencing technologies and a global network of laboratories that turn samples into answers in hours, not weeks.

Now we are expanding that same disruptive model across all of genomics. With the launch of our new RNA-seq service, we are taking a bold step toward our vision to sequence everything, providing scientists everywhere with faster, simpler, and more affordable access to the data that powers discovery.

Every team member at Plasmidsaurus plays a crucial role in driving the future of biotech research. Together, we are building the world’s most efficient sequencing engine that operates overnight, scales globally, and helps scientists make breakthroughs faster than ever before.

Role Overview

Plasmidsaurus is growing quickly, and our San Francisco headquarters needs to keep pace. As SF Site Operations Manager, you make sure the lab and office run smoothly every day so scientists can focus on sequencing, employees have a positive and efficient workplace, and candidates, customers, and visitors have an exceptional experience at our headquarters.

You're the connective tissue that keeps the site running: lab inventory, equipment maintenance, deliveries, and BSL2 safety execution, alongside workplace operations, candidate visits, local vendors, facilities issues, and employee events.

You'll work closely with Procurement to make sure supplies are never a bottleneck. That relationship should feel like a partnership that clears the path, not a gate scientists have to get through.

This is a hands-on operating role for someone who notices what needs fixing, takes ownership quickly, and makes the site feel organized, reliable, and easy to work in

What You'll Do

Own Laboratory Operations

• Own the day-to-day operation of the SF laboratory, ensuring it is organized, well-maintained, fully stocked, and ready to support uninterrupted sequencing operations.

• Manage laboratory organization and operational readiness.

• Manage laboratory inventory and consumable stock levels in partnership with Procurement.

• Coordinate deliveries and receive shipments.

• Coordinate equipment acquisition, installation, preventative maintenance, and repairs.

• Maintain organized, efficient laboratory workspaces.

• Support laboratory budgeting and local operational spending.

• Partner with laboratory teams to identify and resolve operational issues before they disrupt sequencing work.

Own Local Safety Execution

• Own local safety execution so the SF laboratory remains safe, organized, and inspection-ready.

• Execute BSL2 safety procedures, inspections, and documentation, including setup and oversight of a BSL2 room for potentially infectious material.

• Coordinate EH&S activities, including scheduling trainings and documenting chemical and hazardous material inventory.

• Ensure safety equipment is maintained and accessible.

• Partner with the Operations & Facilities teams to implement new compliance initiatives.

• Support laboratory teams during inspections or audits.

Own Office & Workplace Operations

• Own the day-to-day operation of our San Francisco headquarters, creating a workplace that is organized, welcoming, and enables employees to do their best work.

• Manage office supplies and common spaces.

• Coordinate office vendors— cleaning, kitchen, maintenance, security, and related services.

• Serve as the primary contact for the landlord and day-to-day facilities issues.

• Manage incoming mail and deliveries.

• Welcome candidates, customers, and visitors and facilitate their visits.

• Help coordinate onsite interviews and meeting logistics, and ensure guests know their way around the building and space and have what they need.

• Organize SF-based employee events and community-building activities.

• Coordinate light IT logistics such as workstation setup, accessories, and equipment inventory in partnership with the IT team.

Own Site Coordination

• Own the overall operational health of the SF site by coordinating vendors, identifying issues before they become problems, and continuously improving how the site functions as the company grows.

• Coordinate local vendors and contractors.

• Escalate larger facilities projects to the Operations & Facilities team.

• Partner with Operations, Facilities, Procurement, IT, and laboratory leadership to keep the site running smoothly.

• Continuously improve local workflows, communication, and site operations.

What Success Looks Like

The First Three Months

The SF laboratory and office are operating smoothly, with clear ownership of day-to-day operational responsibilities.

Inventory, equipment maintenance, office supplies, deliveries, vendor coordination, and common spaces are organized, predictable, and no longer require regular escalation. Scientists and employees know where to go for operational support and receive timely, reliable help.

Candidates, customers, and visitors experience a welcoming, well-organized headquarters. They know where to go, have the tech and room access they need, and leave with a strong impression of Plasmidsaurus.

Local safety inspections, logs, chemical and hazardous material documentation, and operational checklists are consistently maintained. The BSL2 room for potentially infectious material is operational.

Scientists spend less time solving operational problems and more time focused on sequencing. Equipment downtime and supply interruptions are addressed quickly and no longer create recurring distractions.

Within Six Months

The SF site consistently operates with minimal disruption because inventory, equipment maintenance, workplace operations, vendors, facilities issues, and safety execution are all proactively managed. Headquarters becomes a model for how our labs and offices should run.

Laboratory teams spend minimal time on operational problems and most of their time on sequencing, as equipment downtime keeps dropping through proactive maintenance and vendor management. Operational issues are caught and resolved before they become disruptions.

Workplace operations support a positive employee experience through well-maintained facilities, organized common spaces, reliable onsite support, and thoughtful employee events.

Safety procedures are consistently executed and integrated into normal laboratory operations. Leadership no longer spends meaningful time coordinating day-to-day site operations.

Within One Year

Laboratory and office operations continue to scale with company growth without creating unnecessary administrative burden. Local operational issues are identified and resolved proactively before they impact employees, visitors, laboratory throughput, or site experience.

Employees, candidates, customers, and visitors consistently have a high-quality onsite experience.

The systems supporting laboratory operations, workplace operations, facilities coordination, and local safety execution scale with the company without adding unnecessary complexity.

The SF site is recognized as a reliable, organized, and scalable operation that enables scientific productivity rather than slowing it down and we’re able to leverage processes and approaches from SF to help empower other locations.

What You Bring

Experience

• 2-4 years of experience in laboratory operations, office operations, workplace operations, facilities, or similar operational roles.

• Experience supporting laboratory environments, preferably in biotech or life sciences. Experience with BSL2/BSL3 protocols needed.

• Experience coordinating vendors, contractors, equipment, inventory, deliveries, facilities issues, and workplace operations.

• Experience supporting safety procedures, inspections, documentation, or EH&S activities in a laboratory setting.

• Startup or high-growth company experience strongly preferred.

Skills & Competencies

• Strong organizational skills and the ability to balance many operational priorities simultaneously.

• A customer-service mindset; you enjoy making life easier for others and your wins are based on the success of the team around you.

• Able to quickly build productive relationships with scientists, vendors, facilities teams, employees, candidates, customers, and visitors.

• Efficient in your work and your working relationships, you can quickly get the information or access you need from the team around you to independently move a project or solution forward, extending the capacity of the team, versus impairing it.

• Notices problems before others do and enjoys solving them.

• Comfortable moving between hands-on work, vendor coordination, site support, and process improvement.

• Practical and execution-oriented with strong follow-through.

Ways of Working

Build — You see opportunities to improve how things operate and don't wait to be asked to build a better system, workflow, or schedule. What you put in place is efficient enough to scale as the site grows, without adding unnecessary complexity.

Own — Every part of the site has an owner, and it’s you. You take pride in making complex operations feel effortless for everyone else. You're naturally organized, catch problems before they become emergencies, and take ownership of making things better.

Move — Every day looks different, and you can move from a candidate visit to an equipment repair to a lab shipment to a facilities issue to a safety inspection without losing momentum or missing details. Bias to action, not analysis paralysis.

Participate — You build trust with scientists, vendors, facilities teams, employees, and visitors because you're responsive, practical, and reliable. Your wins are measured by the success of the team around you, not just your own to-do list.

Inspire — You create an environment where people can do their best work because everything around them just works, and help other sites do the same as the company grows.

We encourage you to apply even if your experience doesn't perfectly align with the job description as we seek out diverse and creative perspectives. Team members who love to learn and collaborate in an inclusive environment will thrive with us. We are an equal opportunity employer and do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. If you need additional accommodations to feel comfortable during your interview process, please let us know at [email protected].