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South San Francisco, California, United StatesFounded 2019146+ employeesMAZE
$646M raisedGrowth· last: post ipo equity (Sep 2025)· 5 rounds
Backed by(23 investors)
Deep Track Capital · LeadFrazier Life Sciences · LeadARCH Venture Partners · LeadCity Hill Ventures · LeadMatrix Capital Management · LeadThird Rock Ventures · Lead+9 more

Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular and related metabolic diseases, including obesity. The company is advancing a pipeline using its Compass platform, which allows it to identify and characterize genetic variants in disease and then link those variants to the biological pathways that drive disease in specific patient groups through a process it refers to as variant functionalization. The company’s pipeline is led by two wholly owned lead programs, MZE829 and MZE782, each of which represents a novel precision medicine-based approach for chronic kidney disease. Maze is based in South San Francisco.

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