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Haplotype Labs logo

Haplotype Labs

1 open1 remote
Orinda, California, United StatesFounded 20241+ employeesSeed raisedSeedPrivate
Last round: seed · Jan 2026(2 rounds total)
Personalized prevention using genetics and AI
Backed by(3 investors)
Y CombinatorSoma CapitalSaturnin Pugnet

Haplotype is a startup that improves human health over time by dramatically improving the security, accessibility, and sophistication of population genetics software and polygenic risk scores.

YC W24

About the Company

We are a seed stage startup building the HaploHub. The HaploHub helps genetic testing labs, concierge medical practices, DTC products, and payer/providers to:

  • securely host, manage, and interrogate the genetic data of their population
  • predict disease risk for their patients based on proprietary or publicly available genetic models
  • generate reports and run the most common inference algorithms (phasing, imputation, ibd, etc.) without writing code

Tech Stack

We are developing a cutting edge storage and inference platform for human genetics using python and c on public cloud infrastructure.

Founders

Mike Polcari
Mike Polcari

Mike is the founder of Haplotype Labs. Previously, Mike served as the VP & Chief Architect at 23andMe. Mike's tenure at 23andMe spanned a 15+ year category-defining journey from Series A through IPO. Prior to 23andMe, Mike was an early engineer at Salesforce.com and developed technology at Merrill Lynch. Mike holds a BS in CS from Cornell, a MS in Biomedical Informatics from Stanford, and multiple patents related to cloud computing, security, genetics, and machine learning.

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