# Trust Safety Manager Jobs in San Francisco, CA 200 trust safety manager jobs in San Francisco, CA. Top employers: OpenAI, Astranis, Anthropic, and 5 more. Salaries from $30K–$500K. 200 open roles · page 1 of 14 **Model Policy Manager, National Security** at OpenAI San Francisco | FULL_TIME | USD 207K–335K/yr [Apply](https://zerogtalent.com/ai-jobs/openai/model-policy-manager-national-security-230d7d77-133e-4b87-a7a4-3e8d4e9fdab3) | [JD](https://zerogtalent.com/api/agent/job/model-policy-manager-national-security-230d7d77-133e-4b87-a7a4-3e8d4e9fdab3) **Product Counsel** at Sierra AI San Francisco, CA | FULL_TIME | USD 220K–250K/yr [Apply](https://zerogtalent.com/space-jobs/sierra-ai/product-counsel-91668530-793c-4c84-a909-f64e9e5160a4) | [JD](https://zerogtalent.com/api/agent/job/product-counsel-91668530-793c-4c84-a909-f64e9e5160a4) **Creative Partnerships, Onboarding and Enablement Manager** at OpenAI San Francisco | FULL_TIME | USD 333K–389K/yr [Apply](https://zerogtalent.com/ai-jobs/openai/creative-partnerships-onboarding-and-enablement-manager-20b2d81c-943b-4be7-a304-39c29bf33923) | [JD](https://zerogtalent.com/api/agent/job/creative-partnerships-onboarding-and-enablement-manager-20b2d81c-943b-4be7-a304-39c29bf33923) **Forward Deployed Product Manager** at Infinitus Systems San Francisco Office | FULL_TIME [Apply](https://zerogtalent.com/ai-jobs/infinitus-systems/forward-deployed-product-manager-f6cb1421-81c9-4403-b0d8-b73e1dffdbae) | [JD](https://zerogtalent.com/api/agent/job/forward-deployed-product-manager-f6cb1421-81c9-4403-b0d8-b73e1dffdbae) **Program Manager, National Security Policy Operations** at OpenAI San Francisco | FULL_TIME | USD 171K–190K/yr [Apply](https://zerogtalent.com/ai-jobs/openai/program-manager-national-security-policy-operations-3228eed1-9cb3-4330-82c3-19fb3dbb4408) | [JD](https://zerogtalent.com/api/agent/job/program-manager-national-security-policy-operations-3228eed1-9cb3-4330-82c3-19fb3dbb4408) **Product Manager, Payor Agents** at Infinitus Systems San Francisco Office | FULL_TIME [Apply](https://zerogtalent.com/ai-jobs/infinitus-systems/product-manager-payor-agents-79f919cc-ed08-4bdf-9fb3-db15a962628b) | [JD](https://zerogtalent.com/api/agent/job/product-manager-payor-agents-79f919cc-ed08-4bdf-9fb3-db15a962628b) **Senior Manager, Supplier MDM Operations** at OpenAI San Francisco | FULL_TIME | USD 216K–240K/yr [Apply](https://zerogtalent.com/ai-jobs/openai/senior-manager-supplier-mdm-operations-395e9fe2-4d78-42dd-b3f7-603884915a59) | [JD](https://zerogtalent.com/api/agent/job/senior-manager-supplier-mdm-operations-395e9fe2-4d78-42dd-b3f7-603884915a59) **Account Manager** at Ambience Healthcare Remote - US | Remote | FULL_TIME | USD 232K–290K/yr [Apply](https://zerogtalent.com/ai-jobs/ambience-healthcare/account-manager-54a833ea-83a0-4ac1-9b73-ace9c07ec5a5) | [JD](https://zerogtalent.com/api/agent/job/account-manager-54a833ea-83a0-4ac1-9b73-ace9c07ec5a5) **Engineering Manager - Network Health** at Plaid San Francisco HQ | FULL_TIME | USD 216K–291K/yr [Apply](https://zerogtalent.com/frontier-jobs/plaid/engineering-manager-network-health-72c3cb1d-ec3d-4dd2-8fd4-4bd79e86c1f9) | [JD](https://zerogtalent.com/api/agent/job/engineering-manager-network-health-72c3cb1d-ec3d-4dd2-8fd4-4bd79e86c1f9) **Engineering Manager, Preparedness** at OpenAI San Francisco | FULL_TIME | USD 445K–510K/yr [Apply](https://zerogtalent.com/ai-jobs/openai/engineering-manager-preparedness-c857b732-3556-4b65-8ae9-f64b92091729) | [JD](https://zerogtalent.com/api/agent/job/engineering-manager-preparedness-c857b732-3556-4b65-8ae9-f64b92091729) **Software Engineer, Payments Infrastructure** at Sierra AI San Francisco, CA | FULL_TIME | USD 230K–390K/yr [Apply](https://zerogtalent.com/space-jobs/sierra-ai/software-engineer-payments-infrastructure-50ec6f9a-25f9-44b4-b8cc-50c897e698b3) | [JD](https://zerogtalent.com/api/agent/job/software-engineer-payments-infrastructure-50ec6f9a-25f9-44b4-b8cc-50c897e698b3) **Business Development Lead, Life Sciences** at OpenAI San Francisco | FULL_TIME | USD 400K–445K/yr [Apply](https://zerogtalent.com/ai-jobs/openai/business-development-lead-life-sciences-f42d2e1e-8c2d-47cf-bd29-4b459c06ae1a) | [JD](https://zerogtalent.com/api/agent/job/business-development-lead-life-sciences-f42d2e1e-8c2d-47cf-bd29-4b459c06ae1a) **Legal Response Specialist** at Perplexity San Francisco | FULL_TIME | USD 100K–115K/yr [Apply](https://zerogtalent.com/ai-jobs/perplexity/legal-response-specialist-ffa25e26-9675-4ab1-bc98-325675879e1d) | [JD](https://zerogtalent.com/api/agent/job/legal-response-specialist-ffa25e26-9675-4ab1-bc98-325675879e1d) **Platform Operations Program Manager** at OpenAI San Francisco | FULL_TIME | USD 252K–280K/yr [Apply](https://zerogtalent.com/ai-jobs/openai/platform-operations-program-manager-616ef2ce-3790-432d-9a6d-32abb2f52ff9) | [JD](https://zerogtalent.com/api/agent/job/platform-operations-program-manager-616ef2ce-3790-432d-9a6d-32abb2f52ff9) **Compliance Program Manager — Regulatory Compliance** at OpenAI San Francisco | FULL_TIME | USD 216K–240K/yr [Apply](https://zerogtalent.com/ai-jobs/openai/compliance-program-manager-regulatory-compliance-5f094405-1b54-419b-88b2-df1d7eb16af0) | [JD](https://zerogtalent.com/api/agent/job/compliance-program-manager-regulatory-compliance-5f094405-1b54-419b-88b2-df1d7eb16af0) [Next page](https://zerogtalent.com/trust-safety-manager-jobs-in-san-francisco-ca.md?page=2) --- *Source: [Zero G Talent](https://zerogtalent.com), the job board for space, defense, AI, robotics and frontier-tech companies.*