# Software Engineer Agent Runtime Jobs in San Francisco, CA 200 software engineer agent runtime jobs in San Francisco, CA. Top employers: OpenAI, Astranis, Anthropic, and 5 more. Salaries from $30K–$500K. 200 open roles · page 1 of 14 **Engineering Internship** at Reason Machines San Francisco, CA, US | INTERN [Apply](https://zerogtalent.com/frontier-jobs/reasonmachines-com/engineering-internship-102429) | [JD](https://zerogtalent.com/api/agent/job/engineering-internship-102429) **Software Engineer, Agent Runtime** at Sierra AI San Francisco, CA | FULL_TIME | USD 230K–390K/yr [Apply](https://zerogtalent.com/space-jobs/sierra-ai/software-engineer-agent-runtime-0cb4da3e-3c67-4f14-a84d-956042669275) | [JD](https://zerogtalent.com/api/agent/job/software-engineer-agent-runtime-0cb4da3e-3c67-4f14-a84d-956042669275) **Machine Learning Engineer — Applied AI & Agents** at Cotool San Francisco, CA, US | FULL_TIME | USD 150K–300K/yr [Apply](https://zerogtalent.com/defense-jobs/cotool/machine-learning-engineer-applied-ai-agents-116143) | [JD](https://zerogtalent.com/api/agent/job/machine-learning-engineer-applied-ai-agents-116143) **Founding Product Engineer** at Cotool San Francisco, CA, US | FULL_TIME | USD 150K–300K/yr [Apply](https://zerogtalent.com/defense-jobs/cotool/founding-product-engineer-116142) | [JD](https://zerogtalent.com/api/agent/job/founding-product-engineer-116142) **Software Engineer, API Agents** at OpenAI San Francisco | FULL_TIME | USD 266K–445K/yr [Apply](https://zerogtalent.com/ai-jobs/openai/software-engineer-api-agents-a6ab3111-7092-4da2-a7a6-71e01351bfda) | [JD](https://zerogtalent.com/api/agent/job/software-engineer-api-agents-a6ab3111-7092-4da2-a7a6-71e01351bfda) **Applied AI Engineer, Agents & Robot Learning** at Nori San Francisco, CA, US | FULL_TIME | USD 150K–200K/yr [Apply](https://zerogtalent.com/robotics-jobs/noril1/applied-ai-engineer-agents-robot-learning-117565) | [JD](https://zerogtalent.com/api/agent/job/applied-ai-engineer-agents-robot-learning-117565) **Senior Staff Software Engineer - Agent Marketplace** at Kong San Francisco, California, United States | FULL_TIME | USD 250K–270K/yr [Apply](https://zerogtalent.com/ai-jobs/kong/senior-staff-software-engineer-agent-marketplace-ea7b507b-b249-4cf2-88ea-09fbbaf32acb) | [JD](https://zerogtalent.com/api/agent/job/senior-staff-software-engineer-agent-marketplace-ea7b507b-b249-4cf2-88ea-09fbbaf32acb) **Infrastructure Engineer** at Greptile San Francisco | FULL_TIME | USD 220K–300K/yr [Apply](https://zerogtalent.com/ai-jobs/greptile/infrastructure-engineer-109453) | [JD](https://zerogtalent.com/api/agent/job/infrastructure-engineer-109453) **Software Engineer, Payments Infrastructure** at Sierra AI San Francisco, CA | FULL_TIME | USD 230K–390K/yr [Apply](https://zerogtalent.com/space-jobs/sierra-ai/software-engineer-payments-infrastructure-50ec6f9a-25f9-44b4-b8cc-50c897e698b3) | [JD](https://zerogtalent.com/api/agent/job/software-engineer-payments-infrastructure-50ec6f9a-25f9-44b4-b8cc-50c897e698b3) **Software Engineer, CI/CD & ML Infrastructure** at OpenAI San Francisco | FULL_TIME | USD 318K–485K/yr [Apply](https://zerogtalent.com/ai-jobs/openai/software-engineer-devops-a5dd77a2-9ab1-4165-98aa-c7bb0260985b) | [JD](https://zerogtalent.com/api/agent/job/software-engineer-devops-a5dd77a2-9ab1-4165-98aa-c7bb0260985b) **Founding Engineer, Agent and Data Systems** at Tenor San Francisco, CA, US | FULL_TIME | USD 150K–200K/yr [Apply](https://zerogtalent.com/ai-jobs/tenor/founding-engineer-agent-and-data-systems-117593) | [JD](https://zerogtalent.com/api/agent/job/founding-engineer-agent-and-data-systems-117593) **Senior Platform Engineer** at Wordware San Francisco | FULL_TIME | USD 180K–240K/yr [Apply](https://zerogtalent.com/ai-jobs/wordware/senior-platform-engineer-115019) | [JD](https://zerogtalent.com/api/agent/job/senior-platform-engineer-115019) **Staff Product Manager, AI Management** at Kong San Francisco, California, United States | FULL_TIME | USD 175K–210K/yr [Apply](https://zerogtalent.com/ai-jobs/kong/staff-product-manager-ai-management-72375328-ae8e-4090-9fd3-3580878751e2) | [JD](https://zerogtalent.com/api/agent/job/staff-product-manager-ai-management-72375328-ae8e-4090-9fd3-3580878751e2) **Member of Technical Staff (Software Engineer, Enterprise Agent Evals & Efficiency)** at Perplexity San Francisco | FULL_TIME | USD 220K–405K/yr [Apply](https://zerogtalent.com/ai-jobs/perplexity/member-of-technical-staff-software-engineer-enterprise-agent-evals-efficiency-f3814af2-55a3-49a5-b0cb-67199a2a45fb) | [JD](https://zerogtalent.com/api/agent/job/member-of-technical-staff-software-engineer-enterprise-agent-evals-efficiency-f3814af2-55a3-49a5-b0cb-67199a2a45fb) **Software Engineer, Agent Builder** at Sierra AI San Francisco, CA | FULL_TIME | USD 230K–390K/yr [Apply](https://zerogtalent.com/space-jobs/sierra-ai/software-engineer-agent-builder-200df475-2175-45ce-9510-7d04afabd08d) | [JD](https://zerogtalent.com/api/agent/job/software-engineer-agent-builder-200df475-2175-45ce-9510-7d04afabd08d) [Next page](https://zerogtalent.com/software-engineer-agent-runtime-jobs-in-san-francisco.md?page=2) --- *Source: [Zero G Talent](https://zerogtalent.com), the job board for space, defense, AI, robotics and frontier-tech companies.*