# Senior Software Engineer Sre Jobs in San Francisco, CA 200 senior software engineer sre jobs in San Francisco, CA. Top employers: OpenAI, Astranis, Anthropic, and 5 more. Salaries from $30K–$500K. 200 open roles · page 1 of 14 **Lead Site Reliability Engineer** at UnitedMasters San Francisco | FULL_TIME | USD 195K–240K/yr [Apply](https://zerogtalent.com/ai-jobs/unitedmasters/lead-site-reliability-engineer-8895093002) | [JD](https://zerogtalent.com/api/agent/job/lead-site-reliability-engineer-8895093002) **Senior FPGA Engineer** at Astranis San Francisco | FULL_TIME | USD 175K–240K/yr [Apply](https://zerogtalent.com/space-jobs/astranis/senior-fpga-engineer-4017405006) | [JD](https://zerogtalent.com/api/agent/job/senior-fpga-engineer-4017405006) **Software Engineer, Identity Infrastructure** at OpenAI San Francisco | FULL_TIME | USD 230K–325K/yr [Apply](https://zerogtalent.com/ai-jobs/openai/software-engineer-identity-infrastructure-engineering-551b0d0d-46c2-42fb-bb05-46e2fba8d4db) | [JD](https://zerogtalent.com/api/agent/job/software-engineer-identity-infrastructure-engineering-551b0d0d-46c2-42fb-bb05-46e2fba8d4db) **Software Engineer, Cloud Infrastructure** at Sierra AI San Francisco, CA | FULL_TIME | USD 230K–390K/yr [Apply](https://zerogtalent.com/space-jobs/sierra-ai/software-engineer-cloud-infrastructure-4b28305d-e601-4328-a8f5-9f236bd718bd) | [JD](https://zerogtalent.com/api/agent/job/software-engineer-cloud-infrastructure-4b28305d-e601-4328-a8f5-9f236bd718bd) **Staff Technical Program Manager** at Harvey AI San Francisco | FULL_TIME | USD 200K–275K/yr [Apply](https://zerogtalent.com/ai-jobs/harvey-ai/technical-program-manager-quality-and-reliability-9ea6dcda-7869-4181-b493-2822bbc14097) | [JD](https://zerogtalent.com/api/agent/job/technical-program-manager-quality-and-reliability-9ea6dcda-7869-4181-b493-2822bbc14097) **Senior Software Engineer - Cards** at Mercury San Francisco, CA, New York, NY, Portland, OR, or Remote within Canada or United States | FULL_TIME | USD 167K–208K/yr [Apply](https://zerogtalent.com/frontier-jobs/mercury-banking-for-startups/senior-software-engineer-cards-6233820004) | [JD](https://zerogtalent.com/api/agent/job/senior-software-engineer-cards-6233820004) **Senior Research Infrastructure Engineer** at hud San Francisco / Singapore / Remote (Asia) / Remote (North America) | FULL_TIME | USD 105K–260K/yr [Apply](https://zerogtalent.com/ai-jobs/hud/senior-research-infrastructure-engineer-118494) | [JD](https://zerogtalent.com/api/agent/job/senior-research-infrastructure-engineer-118494) **Senior Software Engineer - Transport Infrastructure** at Atoms San Francisco, CA | FULL_TIME | USD 200K–235K/yr [Apply](https://zerogtalent.com/frontier-jobs/atoms/senior-software-engineer-transport-infrastructure-8909089002) | [JD](https://zerogtalent.com/api/agent/job/senior-software-engineer-transport-infrastructure-8909089002) **Senior Software Engineer - Backend** at HappyRobot San Francisco | FULL_TIME | USD 220K–250K/yr [Apply](https://zerogtalent.com/ai-jobs/happyrobot/senior-software-engineer-backend-224e1cd5-4299-483d-a6d6-70e34130ad94) | [JD](https://zerogtalent.com/api/agent/job/senior-software-engineer-backend-224e1cd5-4299-483d-a6d6-70e34130ad94) **Senior Generalist Engineer** at Greptile San Francisco | FULL_TIME | USD 200K–250K/yr [Apply](https://zerogtalent.com/ai-jobs/greptile/senior-generalist-engineer-109468) | [JD](https://zerogtalent.com/api/agent/job/senior-generalist-engineer-109468) **(Staff / Senior Staff) AI Infra Engineer, Inference Infrastructure** at Together AI San Francisco | FULL_TIME | USD 250K–320K/yr [Apply](https://zerogtalent.com/ai-jobs/together-ai/staff-senior-staff-ai-infra-engineer-inference-infrastructure-5266079007) | [JD](https://zerogtalent.com/api/agent/job/staff-senior-staff-ai-infra-engineer-inference-infrastructure-5266079007) **Senior Software Engineer** at Fuse AI San Francisco, CA, US / Remote (IN; BR; AR) | FULL_TIME | USD 30K–160K/yr [Apply](https://zerogtalent.com/frontier-jobs/fuse-ai/senior-software-engineer-75354) | [JD](https://zerogtalent.com/api/agent/job/senior-software-engineer-75354) **Member of Technical Staff (AI Policy and Strategic Initiatives)** at Perplexity San Francisco | INTERN | USD 200K–330K/yr [Apply](https://zerogtalent.com/ai-jobs/perplexity/member-of-technical-staff-ai-policy-and-strategic-initiatives-c23c4d82-3c53-432b-8a00-2e400ccdf3ea) | [JD](https://zerogtalent.com/api/agent/job/member-of-technical-staff-ai-policy-and-strategic-initiatives-c23c4d82-3c53-432b-8a00-2e400ccdf3ea) **Senior Data Platform Engineer** at Komodo Health San Francisco, CA | FULL_TIME | USD 196K–230K/yr [Apply](https://zerogtalent.com/ai-jobs/komodo-health/senior-data-platform-engineer-8912047002) | [JD](https://zerogtalent.com/api/agent/job/senior-data-platform-engineer-8912047002) **Senior Engineering Manager, Backend Platform** at Harvey AI San Francisco | FULL_TIME | USD 272K–355K/yr [Apply](https://zerogtalent.com/ai-jobs/harvey-ai/senior-engineering-manager-bc2cf43d-c37d-4496-b64e-277ba79ad415) | [JD](https://zerogtalent.com/api/agent/job/senior-engineering-manager-bc2cf43d-c37d-4496-b64e-277ba79ad415) [Next page](https://zerogtalent.com/senior-software-engineer-sre-jobs-in-san-francisco-ca.md?page=2) --- *Source: [Zero G Talent](https://zerogtalent.com), the job board for space, defense, AI, robotics and frontier-tech companies.*