# Senior Software Engineer Infra Systems Jobs in San Francisco, CA 218 senior software engineer infra systems jobs in San Francisco, CA. Top employers: OpenAI, Astranis, Anthropic, and 5 more. Salaries from $30K–$500K. 218 open roles · page 1 of 15 **Software Engineer, Compute Infra** at Cursor San Francisco | FULL_TIME [Apply](https://zerogtalent.com/ai-jobs/cursor/software-engineer-compute-infra-6868de4a-f753-4f10-8dc5-f7aabef03b56) | [JD](https://zerogtalent.com/api/agent/job/software-engineer-compute-infra-6868de4a-f753-4f10-8dc5-f7aabef03b56) **(Staff / Senior Staff) AI Infra Engineer, Inference Infrastructure** at Together AI San Francisco | FULL_TIME | USD 250K–320K/yr [Apply](https://zerogtalent.com/ai-jobs/together-ai/staff-senior-staff-ai-infra-engineer-inference-infrastructure-5266079007) | [JD](https://zerogtalent.com/api/agent/job/staff-senior-staff-ai-infra-engineer-inference-infrastructure-5266079007) **Senior FPGA Engineer** at Astranis San Francisco | FULL_TIME | USD 175K–240K/yr [Apply](https://zerogtalent.com/space-jobs/astranis/senior-fpga-engineer-4017405006) | [JD](https://zerogtalent.com/api/agent/job/senior-fpga-engineer-4017405006) **Software Engineer, Channels and Experiences** at Sierra AI San Francisco, CA | FULL_TIME | USD 230K–390K/yr [Apply](https://zerogtalent.com/space-jobs/sierra-ai/software-engineer-channels-and-experiences-2f372b6b-d163-48bd-b5df-84f9bf2b4dbc) | [JD](https://zerogtalent.com/api/agent/job/software-engineer-channels-and-experiences-2f372b6b-d163-48bd-b5df-84f9bf2b4dbc) **Developer Advocate** at Pinecone San Francisco | Remote | FULL_TIME | USD 140K–240K/yr [Apply](https://zerogtalent.com/ai-jobs/pinecone/developer-advocate-4433b308-1ff4-4b5f-9184-810e5d9844f6) | [JD](https://zerogtalent.com/api/agent/job/developer-advocate-4433b308-1ff4-4b5f-9184-810e5d9844f6) **Engineering Manager, Finance Engineering** at Anthropic San Francisco, CA | Seattle, WA | FULL_TIME | USD 320K–405K/yr [Apply](https://zerogtalent.com/ai-jobs/anthropic/engineering-manager-finance-engineering-5457708008) | [JD](https://zerogtalent.com/api/agent/job/engineering-manager-finance-engineering-5457708008) **Senior Software Engineer - Transport Infrastructure** at Atoms San Francisco, CA | FULL_TIME | USD 200K–235K/yr [Apply](https://zerogtalent.com/frontier-jobs/atoms/senior-software-engineer-transport-infrastructure-8909089002) | [JD](https://zerogtalent.com/api/agent/job/senior-software-engineer-transport-infrastructure-8909089002) **Tinkerer** at Thinking Machines Lab San Francisco | FULL_TIME | USD 300K–350K/yr [Apply](https://zerogtalent.com/ai-jobs/thinking-machines-lab/tinkerer-7b75cf3d-979d-423e-bbb4-652a5d659abb) | [JD](https://zerogtalent.com/api/agent/job/tinkerer-7b75cf3d-979d-423e-bbb4-652a5d659abb) **Staff Software Engineer, Finance Engineering** at Anthropic San Francisco, CA | Seattle, WA | FULL_TIME | USD 320K–405K/yr [Apply](https://zerogtalent.com/ai-jobs/anthropic/staff-software-engineer-finance-engineering-5457716008) | [JD](https://zerogtalent.com/api/agent/job/staff-software-engineer-finance-engineering-5457716008) **Member of Technical Staff, Cekura (San Francisco, In-Person)** at Cekura San Francisco, CA, US | FULL_TIME | USD 150K–200K/yr [Apply](https://zerogtalent.com/ai-jobs/cekura/member-of-technical-staff-cekura-san-francisco-in-person-106505) | [JD](https://zerogtalent.com/api/agent/job/member-of-technical-staff-cekura-san-francisco-in-person-106505) **ML Infra Engineer, Platform** at Physical Intelligence San Francisco | FULL_TIME [Apply](https://zerogtalent.com/robotics-jobs/physical-intelligence/ml-infra-engineer-platform-16093ed0-49de-429e-81d4-6d8b5d715c01) | [JD](https://zerogtalent.com/api/agent/job/ml-infra-engineer-platform-16093ed0-49de-429e-81d4-6d8b5d715c01) **Senior Software Engineer - Cards** at Mercury San Francisco, CA, New York, NY, Portland, OR, or Remote within Canada or United States | FULL_TIME | USD 167K–208K/yr [Apply](https://zerogtalent.com/frontier-jobs/mercury-banking-for-startups/senior-software-engineer-cards-6233820004) | [JD](https://zerogtalent.com/api/agent/job/senior-software-engineer-cards-6233820004) **Senior Research Infrastructure Engineer** at hud San Francisco / Singapore / Remote (Asia) / Remote (North America) | FULL_TIME | USD 105K–260K/yr [Apply](https://zerogtalent.com/ai-jobs/hud/senior-research-infrastructure-engineer-118494) | [JD](https://zerogtalent.com/api/agent/job/senior-research-infrastructure-engineer-118494) **Software Engineer, Core Infrastructure (Mid-Senior level)** at Zip San Francisco | FULL_TIME | USD 165K–240K/yr [Apply](https://zerogtalent.com/ai-jobs/zip/software-engineer-core-infrastructure-mid-senior-level-115070) | [JD](https://zerogtalent.com/api/agent/job/software-engineer-core-infrastructure-mid-senior-level-115070) **Forward Deployed Engineer (US)** at Cekura San Francisco, CA, US | FULL_TIME | USD 100K–180K/yr [Apply](https://zerogtalent.com/ai-jobs/cekura/forward-deployed-engineer-us-95171) | [JD](https://zerogtalent.com/api/agent/job/forward-deployed-engineer-us-95171) [Next page](https://zerogtalent.com/senior-software-engineer-infra-systems-jobs-in-san-francisco.md?page=2) --- *Source: [Zero G Talent](https://zerogtalent.com), the job board for space, defense, AI, robotics and frontier-tech companies.*