# Senior Scientific Software Engineer Jobs in San Francisco, CA 200 senior scientific software engineer jobs in San Francisco, CA. Top employers: OpenAI, Astranis, Anthropic, and 5 more. Salaries from $30K–$500K. 200 open roles · page 1 of 14 **Business Development Lead, Life Sciences** at OpenAI San Francisco | FULL_TIME | USD 400K–445K/yr [Apply](https://zerogtalent.com/ai-jobs/openai/business-development-lead-life-sciences-f42d2e1e-8c2d-47cf-bd29-4b459c06ae1a) | [JD](https://zerogtalent.com/api/agent/job/business-development-lead-life-sciences-f42d2e1e-8c2d-47cf-bd29-4b459c06ae1a) **Software Engineer, Compute Infra** at Cursor San Francisco | FULL_TIME [Apply](https://zerogtalent.com/ai-jobs/cursor/software-engineer-compute-infra-6868de4a-f753-4f10-8dc5-f7aabef03b56) | [JD](https://zerogtalent.com/api/agent/job/software-engineer-compute-infra-6868de4a-f753-4f10-8dc5-f7aabef03b56) **General Counsel** at Plasmidsaurus San Francisco | FULL_TIME | USD 275K–300K/yr [Apply](https://zerogtalent.com/frontier-jobs/plasmidsaurus/general-counsel-dba3ba98-c75e-4de9-8a82-bf5ec005f772) | [JD](https://zerogtalent.com/api/agent/job/general-counsel-dba3ba98-c75e-4de9-8a82-bf5ec005f772) **Strategic Finance** at Runway San Francisco, CA | Remote | FULL_TIME | USD 180K–280K/yr [Apply](https://zerogtalent.com/ai-jobs/runway/strategic-finance-40598dd0-234b-4256-b2a2-91608b66b8aa) | [JD](https://zerogtalent.com/api/agent/job/strategic-finance-40598dd0-234b-4256-b2a2-91608b66b8aa) **Data Program Manager, Science** at OpenAI San Francisco | FULL_TIME | USD 207K–230K/yr [Apply](https://zerogtalent.com/ai-jobs/openai/data-program-manager-science-2bdd1b8b-2883-40fb-b006-583959ad4c5f) | [JD](https://zerogtalent.com/api/agent/job/data-program-manager-science-2bdd1b8b-2883-40fb-b006-583959ad4c5f) **Senior FPGA Engineer** at Astranis San Francisco | FULL_TIME | USD 175K–240K/yr [Apply](https://zerogtalent.com/space-jobs/astranis/senior-fpga-engineer-4017405006) | [JD](https://zerogtalent.com/api/agent/job/senior-fpga-engineer-4017405006) **Mechanical Engineering Co-op/Intern (Spring 2027)** at Multiply Labs San Francisco | INTERN [Apply](https://zerogtalent.com/robotics-jobs/multiply-labs/mechanical-engineering-co-op-intern-spring-2027-4a95d36f-6ea3-4044-a6ab-5c2c1d4997a5) | [JD](https://zerogtalent.com/api/agent/job/mechanical-engineering-co-op-intern-spring-2027-4a95d36f-6ea3-4044-a6ab-5c2c1d4997a5) **Field Marketing Specialist** at Plasmidsaurus San Francisco | FULL_TIME | USD 100K–130K/yr [Apply](https://zerogtalent.com/frontier-jobs/plasmidsaurus/field-marketing-specialist-e44b7ec6-039d-4db4-9751-3b090411e88b) | [JD](https://zerogtalent.com/api/agent/job/field-marketing-specialist-e44b7ec6-039d-4db4-9751-3b090411e88b) **Machine Learning Engineer, Implicit Signals** at OpenAI San Francisco | FULL_TIME | USD 381K–510K/yr [Apply](https://zerogtalent.com/ai-jobs/openai/machine-learning-engineer-implicit-signals-a01fc9ed-de08-4326-9206-4ee3f08000dc) | [JD](https://zerogtalent.com/api/agent/job/machine-learning-engineer-implicit-signals-a01fc9ed-de08-4326-9206-4ee3f08000dc) **Software Engineer, Extensibility Platform** at Benchling San Francisco, CA | FULL_TIME | USD 148K–235K/yr [Apply](https://zerogtalent.com/frontier-jobs/benchling/software-engineer-extensibility-platform-a0b8e8ed-99ff-4f80-a933-34f9a12e06fa) | [JD](https://zerogtalent.com/api/agent/job/software-engineer-extensibility-platform-a0b8e8ed-99ff-4f80-a933-34f9a12e06fa) **Head of Product** at Multiply Labs San Francisco | FULL_TIME | USD 220K–290K/yr [Apply](https://zerogtalent.com/robotics-jobs/multiply-labs/head-of-product-7117520e-6a09-4321-9dcc-b2d1e7708f2e) | [JD](https://zerogtalent.com/api/agent/job/head-of-product-7117520e-6a09-4321-9dcc-b2d1e7708f2e) **Senior Software Engineer - Transport Infrastructure** at Atoms San Francisco, CA | FULL_TIME | USD 200K–235K/yr [Apply](https://zerogtalent.com/frontier-jobs/atoms/senior-software-engineer-transport-infrastructure-8909089002) | [JD](https://zerogtalent.com/api/agent/job/senior-software-engineer-transport-infrastructure-8909089002) **Senior Software Engineer - Backend** at HappyRobot San Francisco | FULL_TIME | USD 220K–250K/yr [Apply](https://zerogtalent.com/ai-jobs/happyrobot/senior-software-engineer-backend-224e1cd5-4299-483d-a6d6-70e34130ad94) | [JD](https://zerogtalent.com/api/agent/job/senior-software-engineer-backend-224e1cd5-4299-483d-a6d6-70e34130ad94) **Senior Generalist Engineer** at Greptile San Francisco | FULL_TIME | USD 200K–250K/yr [Apply](https://zerogtalent.com/ai-jobs/greptile/senior-generalist-engineer-109468) | [JD](https://zerogtalent.com/api/agent/job/senior-generalist-engineer-109468) **Forward Deployed Engineer, Battery Engineering** at Ohm San Francisco, CA / Remote (US) | FULL_TIME [Apply](https://zerogtalent.com/ai-jobs/ohm/forward-deployed-engineer-battery-engineering-100839) | [JD](https://zerogtalent.com/api/agent/job/forward-deployed-engineer-battery-engineering-100839) [Next page](https://zerogtalent.com/senior-scientific-software-engineer-jobs-in-san-francisco-ca.md?page=2) --- *Source: [Zero G Talent](https://zerogtalent.com), the job board for space, defense, AI, robotics and frontier-tech companies.*