# Senior Engineer Backend Infra Jobs in San Francisco, CA

200 senior engineer backend infra jobs in San Francisco, CA. Top employers: OpenAI, Astranis, Anthropic, and 5 more. Salaries from $30K–$500K.

200 open roles · page 1 of 14

**Senior Software Engineer - Backend** at HappyRobot
San Francisco | FULL_TIME | USD 220K–250K/yr
[Apply](https://zerogtalent.com/ai-jobs/happyrobot/senior-software-engineer-backend-224e1cd5-4299-483d-a6d6-70e34130ad94) | [JD](https://zerogtalent.com/api/agent/job/senior-software-engineer-backend-224e1cd5-4299-483d-a6d6-70e34130ad94)

**Senior Engineering Manager, Backend Platform** at Harvey AI
San Francisco | FULL_TIME | USD 272K–355K/yr
[Apply](https://zerogtalent.com/ai-jobs/harvey-ai/senior-engineering-manager-bc2cf43d-c37d-4496-b64e-277ba79ad415) | [JD](https://zerogtalent.com/api/agent/job/senior-engineering-manager-bc2cf43d-c37d-4496-b64e-277ba79ad415)

**Senior Software Engineer** at Orthogonal
San Francisco, CA | FULL_TIME
[Apply](https://zerogtalent.com/frontier-jobs/orthogonal/senior-software-engineer-114623) | [JD](https://zerogtalent.com/api/agent/job/senior-software-engineer-114623)

**Software Engineer, Channels and Experiences** at Sierra AI
San Francisco, CA | FULL_TIME | USD 230K–390K/yr
[Apply](https://zerogtalent.com/space-jobs/sierra-ai/software-engineer-channels-and-experiences-2f372b6b-d163-48bd-b5df-84f9bf2b4dbc) | [JD](https://zerogtalent.com/api/agent/job/software-engineer-channels-and-experiences-2f372b6b-d163-48bd-b5df-84f9bf2b4dbc)

**Engineering Manager, Finance Engineering** at Anthropic
San Francisco, CA | Seattle, WA | FULL_TIME | USD 320K–405K/yr
[Apply](https://zerogtalent.com/ai-jobs/anthropic/engineering-manager-finance-engineering-5457708008) | [JD](https://zerogtalent.com/api/agent/job/engineering-manager-finance-engineering-5457708008)

**Software Engineer - Backend** at HappyRobot
San Francisco | FULL_TIME | USD 180K–250K/yr
[Apply](https://zerogtalent.com/ai-jobs/happyrobot/software-engineer-backend-019a38ba-756c-4c5c-8742-756f101b38c4) | [JD](https://zerogtalent.com/api/agent/job/software-engineer-backend-019a38ba-756c-4c5c-8742-756f101b38c4)

**(Staff / Senior Staff) AI Infra Engineer, Inference Infrastructure** at Together AI
San Francisco | FULL_TIME | USD 250K–320K/yr
[Apply](https://zerogtalent.com/ai-jobs/together-ai/staff-senior-staff-ai-infra-engineer-inference-infrastructure-5266079007) | [JD](https://zerogtalent.com/api/agent/job/staff-senior-staff-ai-infra-engineer-inference-infrastructure-5266079007)

**Staff Software Engineer, Finance Engineering** at Anthropic
San Francisco, CA | Seattle, WA | FULL_TIME | USD 320K–405K/yr
[Apply](https://zerogtalent.com/ai-jobs/anthropic/staff-software-engineer-finance-engineering-5457716008) | [JD](https://zerogtalent.com/api/agent/job/staff-software-engineer-finance-engineering-5457716008)

**Member of Technical Staff, Cekura (San Francisco, In-Person)** at Cekura
San Francisco, CA, US | FULL_TIME | USD 150K–200K/yr
[Apply](https://zerogtalent.com/ai-jobs/cekura/member-of-technical-staff-cekura-san-francisco-in-person-106505) | [JD](https://zerogtalent.com/api/agent/job/member-of-technical-staff-cekura-san-francisco-in-person-106505)

**Founding Engineer** at Prescience
San Francisco, CA, US | FULL_TIME | USD 180K–250K/yr
[Apply](https://zerogtalent.com/frontier-jobs/prescience/founding-engineer-107167) | [JD](https://zerogtalent.com/api/agent/job/founding-engineer-107167)

**Principal Software Engineer, Full Stack — Codex** at OpenAI
San Francisco | FULL_TIME | USD 459K–536K/yr
[Apply](https://zerogtalent.com/ai-jobs/openai/principal-software-engineer-full-stack-codex-74842880-e750-4664-9e2e-83b4c96c5a03) | [JD](https://zerogtalent.com/api/agent/job/principal-software-engineer-full-stack-codex-74842880-e750-4664-9e2e-83b4c96c5a03)

**Developer Advocate** at Pinecone
San Francisco | Remote | FULL_TIME | USD 140K–240K/yr
[Apply](https://zerogtalent.com/ai-jobs/pinecone/developer-advocate-4433b308-1ff4-4b5f-9184-810e5d9844f6) | [JD](https://zerogtalent.com/api/agent/job/developer-advocate-4433b308-1ff4-4b5f-9184-810e5d9844f6)

**Member of Technical Staff, Envoy Response** at Envoy
San Francisco, CA | FULL_TIME | USD 205K–225K/yr
[Apply](https://zerogtalent.com/ai-jobs/envoy/member-of-technical-staff-envoy-response-3723e967-2b5e-415c-8cab-3e30e5460154) | [JD](https://zerogtalent.com/api/agent/job/member-of-technical-staff-envoy-response-3723e967-2b5e-415c-8cab-3e30e5460154)

**Engineering Manager, Preparedness** at OpenAI
San Francisco | FULL_TIME | USD 445K–510K/yr
[Apply](https://zerogtalent.com/ai-jobs/openai/engineering-manager-preparedness-c857b732-3556-4b65-8ae9-f64b92091729) | [JD](https://zerogtalent.com/api/agent/job/engineering-manager-preparedness-c857b732-3556-4b65-8ae9-f64b92091729)

**Senior Software Engineer, Data Services** at Alchemy
San Francisco | FULL_TIME | USD 205K–230K/yr
[Apply](https://zerogtalent.com/ai-jobs/alchemy-com/senior-software-engineer-data-services-bca25725-dbdf-4786-9af9-aa793766d2b5) | [JD](https://zerogtalent.com/api/agent/job/senior-software-engineer-data-services-bca25725-dbdf-4786-9af9-aa793766d2b5)

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