# Manager Hardware System Safety Jobs in San Francisco, CA

200 manager hardware system safety jobs in San Francisco, CA. Top employers: OpenAI, Astranis, Anthropic, and 5 more. Salaries from $30K–$500K.

200 open roles · page 1 of 14

**Model Policy Manager, National Security** at OpenAI
San Francisco | FULL_TIME | USD 207K–335K/yr
[Apply](https://zerogtalent.com/ai-jobs/openai/model-policy-manager-national-security-230d7d77-133e-4b87-a7a4-3e8d4e9fdab3) | [JD](https://zerogtalent.com/api/agent/job/model-policy-manager-national-security-230d7d77-133e-4b87-a7a4-3e8d4e9fdab3)

**Compliance Program Manager — Regulatory Compliance** at OpenAI
San Francisco | FULL_TIME | USD 216K–240K/yr
[Apply](https://zerogtalent.com/ai-jobs/openai/compliance-program-manager-regulatory-compliance-5f094405-1b54-419b-88b2-df1d7eb16af0) | [JD](https://zerogtalent.com/api/agent/job/compliance-program-manager-regulatory-compliance-5f094405-1b54-419b-88b2-df1d7eb16af0)

**Researcher, Misalignment Monitoring Lead** at OpenAI
San Francisco | FULL_TIME | USD 380K–500K/yr
[Apply](https://zerogtalent.com/ai-jobs/openai/researcher-misalignment-monitoring-lead-c955617d-f465-4f7a-b57c-98284fd14777) | [JD](https://zerogtalent.com/api/agent/job/researcher-misalignment-monitoring-lead-c955617d-f465-4f7a-b57c-98284fd14777)

**Machine Shop Manager** at Astro Mechanica
San Francisco | FULL_TIME | USD 165K–210K/yr
[Apply](https://zerogtalent.com/space-jobs/astro-mechanica/machine-shop-lead-18cb86d7-069e-4d1c-b6ae-1ce1f224932f) | [JD](https://zerogtalent.com/api/agent/job/machine-shop-lead-18cb86d7-069e-4d1c-b6ae-1ce1f224932f)

**Engineering Manager, Preparedness** at OpenAI
San Francisco | FULL_TIME | USD 445K–510K/yr
[Apply](https://zerogtalent.com/ai-jobs/openai/engineering-manager-preparedness-c857b732-3556-4b65-8ae9-f64b92091729) | [JD](https://zerogtalent.com/api/agent/job/engineering-manager-preparedness-c857b732-3556-4b65-8ae9-f64b92091729)

**Events Manager, Business** at OpenAI
San Francisco | FULL_TIME | USD 240K–266K/yr
[Apply](https://zerogtalent.com/ai-jobs/openai/events-manager-business-744844e1-f426-463c-b615-91823f0cd867) | [JD](https://zerogtalent.com/api/agent/job/events-manager-business-744844e1-f426-463c-b615-91823f0cd867)

**Head of Enterprise Risk Management** at OpenAI
San Francisco | FULL_TIME | USD 216K–295K/yr
[Apply](https://zerogtalent.com/ai-jobs/openai/head-of-enterprise-risk-management-db40bc4f-c7fb-47d5-a7cc-918fb8b1f815) | [JD](https://zerogtalent.com/api/agent/job/head-of-enterprise-risk-management-db40bc4f-c7fb-47d5-a7cc-918fb8b1f815)

**Senior Software Engineer - Transport Infrastructure** at Atoms
San Francisco, CA | FULL_TIME | USD 200K–235K/yr
[Apply](https://zerogtalent.com/frontier-jobs/atoms/senior-software-engineer-transport-infrastructure-8909089002) | [JD](https://zerogtalent.com/api/agent/job/senior-software-engineer-transport-infrastructure-8909089002)

**Events Manager, Brand & Communications** at OpenAI
San Francisco | FULL_TIME | USD 240K–266K/yr
[Apply](https://zerogtalent.com/ai-jobs/openai/events-manager-brand-communications-2ffdcfea-7a7c-46a1-a3d7-e9a2c598258b) | [JD](https://zerogtalent.com/api/agent/job/events-manager-brand-communications-2ffdcfea-7a7c-46a1-a3d7-e9a2c598258b)

**Software Engineer, CI/CD & ML Infrastructure** at OpenAI
San Francisco | FULL_TIME | USD 318K–485K/yr
[Apply](https://zerogtalent.com/ai-jobs/openai/software-engineer-devops-a5dd77a2-9ab1-4165-98aa-c7bb0260985b) | [JD](https://zerogtalent.com/api/agent/job/software-engineer-devops-a5dd77a2-9ab1-4165-98aa-c7bb0260985b)

**Business Development Lead, Life Sciences** at OpenAI
San Francisco | FULL_TIME | USD 400K–445K/yr
[Apply](https://zerogtalent.com/ai-jobs/openai/business-development-lead-life-sciences-f42d2e1e-8c2d-47cf-bd29-4b459c06ae1a) | [JD](https://zerogtalent.com/api/agent/job/business-development-lead-life-sciences-f42d2e1e-8c2d-47cf-bd29-4b459c06ae1a)

**Head of Product** at Multiply Labs
San Francisco | FULL_TIME | USD 220K–290K/yr
[Apply](https://zerogtalent.com/robotics-jobs/multiply-labs/head-of-product-7117520e-6a09-4321-9dcc-b2d1e7708f2e) | [JD](https://zerogtalent.com/api/agent/job/head-of-product-7117520e-6a09-4321-9dcc-b2d1e7708f2e)

**Program Manager, National Security Policy Operations** at OpenAI
San Francisco | FULL_TIME | USD 171K–190K/yr
[Apply](https://zerogtalent.com/ai-jobs/openai/program-manager-national-security-policy-operations-3228eed1-9cb3-4330-82c3-19fb3dbb4408) | [JD](https://zerogtalent.com/api/agent/job/program-manager-national-security-policy-operations-3228eed1-9cb3-4330-82c3-19fb3dbb4408)

**Principal Software Engineer, Full Stack — Codex** at OpenAI
San Francisco | FULL_TIME | USD 459K–536K/yr
[Apply](https://zerogtalent.com/ai-jobs/openai/principal-software-engineer-full-stack-codex-74842880-e750-4664-9e2e-83b4c96c5a03) | [JD](https://zerogtalent.com/api/agent/job/principal-software-engineer-full-stack-codex-74842880-e750-4664-9e2e-83b4c96c5a03)

**Applied Scientist, Product Policy** at OpenAI
San Francisco | FULL_TIME | USD 207K–230K/yr
[Apply](https://zerogtalent.com/ai-jobs/openai/applied-scientist-product-policy-6ef9babb-e210-496f-a004-fed919a9ed2d) | [JD](https://zerogtalent.com/api/agent/job/applied-scientist-product-policy-6ef9babb-e210-496f-a004-fed919a9ed2d)

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*Source: [Zero G Talent](https://zerogtalent.com), the job board for space, defense, AI, robotics and frontier-tech companies.*