# Senior Mechanical Design Engineer

**Company:** [SiPhox Health](https://zerogtalent.com/frontier-companies/siphox-health)
**Location:** Burlington, MA, US
**Work mode:** On-site
**Seniority:** Mid
**Employment type:** Full Time
**Salary:** USD 100K–200K/yr
**Category:** Mechanical
**Listed:** 2026-09-23

[View and apply on Zero G Talent](https://zerogtalent.com/frontier-jobs/siphox-health/senior-mechanical-design-engineer-111653)

## What you'll do

- Lead mechanical design for medical device subsystems
- Design and review parts for injection molding
- Plan and execute engineering tests to validate designs
- Create 3D and 2D MCAD models per standards
- Mentor engineers on MCAD, DFM/DFA, and verification

## What you need

- 3+ yrs mechanical design experience
- Expert MCAD user; injection molding expertise
- Experience scaling products from prototype to volume
- Mechanical assembly: ultrasonic welding, laser welding, adhesives
- Tolerance studies and design verification experience

## Job description

### **About us**

SiPhox Health is building a first-of-its-kind consumer diagnostics platform that brings complex biochemical analyses into the home through integrated silicon photonics, microfluidics, embedded systems, and advanced assay development. Our chip-based solution integrates state-of-the-art biochemistry, photonics, electronics, and microfluidics to deliver the power of large laboratory instruments in a portable device.

### **The role**

You will be hands on designing and building the first of its kind home testing system. This person will directly own key parts of the system, with a wide scope to have an impact. You will work closely with the production teams to create systems that are elegant to use, but also manufacturable at scale.

### **Responsibilities**

-   Lead mechanical designs for defined subsystems of medical and diagnostic devices, ensuring functionality, reliability, and manufacturability
-   Design and review parts and assemblies optimized for high-volume injection molding and automated assembly methods
-   Apply rapid prototyping techniques to accelerate product development and iteration, with minimal guidance
-   Plan and execute engineering tests to validate designs and improve performance
-   Create and review detailed design specifications, including 3D and 2D MCAD models following ASME Y14.5 or ISO 8015 standards
-   Closely collaborate with cross-functional teams, including manufacturing engineers and scientists, often owning the mechanical side of complex technical challenges
-   Lead root cause analysis and drive design or process changes to enhance product quality and performance
-   Own system design, system and sub-system requirements and verification plans for your subsystems
-   Mentor Mechanical Design Engineers on MCAD practices, DFM/DFA, and design-verification approach
-   Review other engineers' designs and drawings for manufacturability and compliance with design standards
-   Take a leading role in supplier and vendor conversations for the components/subsystems you own

### **What we’re looking for**

-   Deep knowledge of the challenges of scaling products from prototype to high volume production
-   Real experience working with pilot and full volume production systems, implementing quality controls and maximizing the product’s quality and yield
-   Excellent knowledge of injection molding design, including tolerance studies
-   Excellent knowledge of mechanical assembly techniques, including ultrasonic welding, laser welding, clip design and adhesives
-   Creative problem solver
-   Expert MCAD user

### **Nice to have**

-   Demonstrated ability to design mechanical mechanisms, from concepting through to volume production
-   Experience in medical devices, or with ISO 13485, ISO 14971, or other design controls process
-   Experience working at a manufacturing site, as a process, test or tool engineer
-   Optics, photonics, fluidics, or microfluidics exposure
-   Experience in SolidWorks and OnShape

### **Employment Details**

**Department:** Product Engineering

**Work location:** Burlington, MA (on-site), with some travel to manufacturing sites in the US, Europe and Asia. Trips typically for 1-2 weeks in duration as required.

**Salary Range:** $100,000 – $200,000 (depending on experience)

### **Benefits:**

-   401K
-   Health Insurance
-   Dental Insurance
-   Vision Insurance
-   Health Savings Account
-   Health Flexible Savings Account
-   Dependent Care Flexible Savings Account
-   Life Insurance
-   Paid Time Off
-   Parental Leave
-   Long Term Disability 
-   Equity
-   Gym Membership (Lifetime Fitness — one block from the office)

### **Physical Requirements**

-   Ability to lift up to 20 pounds.
-   Ability to do dexterous tasks with hands, e.g. manual assembly with small tools, soldering
-   This role involves physical activity and routine handling of chemicals. Candidates must adhere to all laboratory safety protocols and be comfortable using appropriate personal protective equipment (PPE).

### **Who Thrives Here**

This role is a strong fit for someone who takes ownership without being asked, is energized by variety rather than routine. They are highly motivated by SiPhox’s mission.

### **Why Join SiPhox Health**

-   Help bring a first-of-its-kind at-home diagnostics platform to market.
-   Work alongside multidisciplinary engineering and scientific teams solving complex technical challenges.
-   Competitive compensation, equity, and benefits (including Lifetime Fitness membership).

### **Equal Opportunity Employer**

SiPhox Health is an equal opportunity employer committed to building an inclusive workplace. Applicants of all backgrounds and experiences are encouraged to apply.

## Other open roles at SiPhox Health

- [Manager, Clinical & Product Operations](https://zerogtalent.com/frontier-jobs/siphox-health/manager-clinical-product-operations-117132) — Burlington, MA
- [Senior Customer Support Specialist and Trainer](https://zerogtalent.com/frontier-jobs/siphox-health/senior-customer-support-specialist-and-trainer-117102) — Burlington, MA / Remote
- [Customer Support Lead](https://zerogtalent.com/frontier-jobs/siphox-health/customer-support-lead-117042) — Burlington, MA, US / Remote
- [System Integration & Test Engineer](https://zerogtalent.com/frontier-jobs/siphox-health/system-integration-test-engineer-111719) — Burlington, MA, US
- [Head of Consumer Experience; Home blood testing](https://zerogtalent.com/frontier-jobs/siphox-health/head-of-consumer-experience-home-blood-testing-109475) — Boston, MA, US

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*Source: [Zero G Talent](https://zerogtalent.com), the job board for space, defense, AI, robotics and frontier-tech companies.*
